description
specification
resources
service description
bgi genomics has extensive experience in the field of targeted metabolomics spanning accurate quantification of target metabolites, verification of hypothesis by untargeted metabolomics or other omics, and metabolic model study for specific metabolites¹.
project workflow
list of targeted metabolomic panels
| category of targeted metabolites | number of metabolites |
|---|---|
| amino acid | 20 |
| water-soluble vitamin | 5 |
| fat-soluble vitamin | 5 |
| steroid hormone | 13 |
| bile acid | 15/45 |
| trimethyamine oxide | 6 |
| short-chain fatty acids | 7 |
| neurotransmitter | 39 |
| trace elements and heavy metals | 18 |
| homocysteine metabolism | 9 |
| plant hormone | 32 |
references
[1] liu r., et al., gut microbiome and serum metabolome alterations in obesity and after weight-loss intervention. nat med, 2017. 23(7): p. 859-868.
how to order
mass spectrometry service specification
targeted metabolomics services are performed using lc-ms, gc-ms and icp-ms.
sample preparation and services
- custom-developed uplc-mrm/ms methods combine isotope internal standard technology
- using lc-ms (sciex qtrap 4500/5500/6500 and waters xevo tq-s), gc-ms (thermo tsq 9000) and icp-ms (agilent 7700) to increase the scope of detection
quality standard
- summary includes all methods and data analysis
- reports provided in excel or pdf format; raw files available upon request
turn around time
- typical 5-7 weeks after sample receipt for raw data delivery
sample requirements
please contact your bgi genomics account representative for details for your samples.
data analysis
- data analysis performed with metax1 and bgi genomics library
- data quality control
- standard curves
- quantification results